Factors Influencing Clinical Trial Participation for Adult and Pediatric Patients with Cystic Fibrosis

Abstract

There remains a limited understanding of the factors influencing clinical trial participation for individuals with Cystic Fibrosis (CF). A comprehensive survey was developed to examine the interests, preferences, and barriers/facilitators to research and clinical trial participation for CF patients. A consecutive sample of 198 CF adults attending the St. Paul’s Hospital CF Clinic and parents of children with CF attending the BC Children’s Hospital CF Clinic from Vancouver, Canada were surveyed. Parents of pediatric patients were less comfortable with blood collection, required more safety data prior to participating, and were more concerned about potential side effects. Very few respondents (<10%) appeared able/willing to fulfill the typical requirements to participate in a phase 1 clinical trial. Overall, there were more similarities than differences between the responses of adult and parents of pediatric CF patients. The patient-centered information can be used to inform the design of future clinical trials to enhance feasibility.

Publication
Journal of Cystic Fibrosis (in-press)
Click the Cite button above to demo the feature to enable visitors to import publication metadata into their reference management software.
Click the Slides button above to demo Academic’s Markdown slides feature.